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・ Retinite
・ Retinitis
・ Retinitis pigmentosa
・ Retinitis pigmentosa GTPase regulator
・ Retinitis Pigmentosa International
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・ Retinoblastoma protein
・ Retinoblastoma-like protein 1
・ Retinoblastoma-like protein 2
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・ Retinoic acid
・ Retinoic acid receptor
Retinoic acid receptor alpha
・ Retinoic acid receptor beta
・ Retinoic acid receptor gamma
・ Retinoic acid syndrome
・ Retinoic acid-inducible orphan G protein-coupled receptor
・ Retinoid
・ Retinoid receptor
・ Retinoid X receptor
・ Retinoid X receptor alpha
・ Retinoid X receptor beta
・ Retinoid X receptor gamma
・ Retinol
・ Retinol binding protein
・ Retinol binding protein 4
・ Retinol dehydrogenase


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Retinoic acid receptor alpha : ウィキペディア英語版
Retinoic acid receptor alpha

Retinoic acid receptor alpha (RAR-α), also known as NR1B1 (nuclear receptor subfamily 1, group B, member 1) is a nuclear receptor that in humans is encoded by the ''RARA'' gene.
== Function ==

Retinoid signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor (RXR), which form RXR/RAR heterodimers. In the absence of ligand, DNA-bound RXR/RARA represses transcription by recruiting the corepressors NCOR1, SMRT (NCOR2), and histone deacetylase. When ligand binds to the complex, it induces a conformational change allowing the recruitment of coactivators, histone acetyltransferases, and the basic transcription machinery.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5914 )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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